TNNC1 Rabbit Polyclonal Antibody (CAB1927)
- SKU:
- CAB1927
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TNNC1 Rabbit Polyclonal Antibody |
SKU: | CAB1927 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC1 (NP_003271.1). |
Sequence: | MDDI YKAA VEQL TEEQ KNEF KAAF DIFV LGAE DGCI STKE LGKV MRML GQNP TPEE LQEM IDEV DEDG SGTV DFDE FLVM MVRC MKDD SKGK SEEE LSDL FRMF DKNA DGYI DLDE LKIM LQAT GETI TEDD IEEL MKDG DKNN DGRI DYDE FLEF MKGV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC1 |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Purification Method: | Affinity purification |
Gene ID: | 7134 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |