TNN Antibody (PACO18957)
- SKU:
- PACO18957
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TNN Antibody (PACO18957)
The TNN Antibody (PAC018957) is a polyclonal antibody developed for research purposes involving the TNN protein. The antibody, produced through immunization of rabbits, specifically targets the TNN protein and is highly reactive with human samples. Validated for use in Western blot applications, this antibody enables the detection and analysis of TNN in various cell types, making it ideal for studies in molecular biology and cellular research.TNN, also known as a protein encoded by tenascin N, plays a crucial role in cellular adhesion and migration processes.
Its involvement in cell signaling and tissue development makes it a significant target for research into various physiological and pathological conditions. Understanding the functions and interactions of TNN can provide valuable insights for studies on cell behavior, tissue regeneration, and disease mechanisms.Overall, the TNN Antibody (PAC018957) offers researchers a reliable tool for investigating the functions and roles of TNN in various biological processes, contributing to advancements in biomedical research and potential therapeutic developments.
| Antibody Name: | TNN Antibody (PACO18957) |
| Antibody SKU: | PACO18957 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:3000-1:10000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human TNN |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18957(TNN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18957(TNN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
| Synonyms: | tenascin N |
| UniProt Protein Function: | TNN: Involved in neurite outgrowth and cell migration in hippocampal explants. Belongs to the tenascin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Extracellular matrix Chromosomal Location of Human Ortholog: 1q23-q24 Cellular Component: proteinaceous extracellular matrix; cell surface Molecular Function:integrin binding; identical protein binding Biological Process: cell migration; axonogenesis; cell-matrix adhesion; cell growth |
| UniProt Code: | Q9UQP3 |
| NCBI GenInfo Identifier: | 81175198 |
| NCBI Gene ID: | 63923 |
| NCBI Accession: | Q9UQP3.2 |
| UniProt Secondary Accession: | Q9UQP3,Q5R360, B9EGP3, |
| UniProt Related Accession: | Q9UQP3 |
| Molecular Weight: | 144,034 Da |
| NCBI Full Name: | Tenascin-N |
| NCBI Synonym Full Names: | tenascin N |
| NCBI Official Symbol: | TNNÂ Â |
| NCBI Official Synonym Symbols: | TN-WÂ Â |
| NCBI Protein Information: | tenascin-N; TN-N |
| UniProt Protein Name: | Tenascin-N |
| Protein Family: | Tenascin |
| UniProt Gene Name: | TNNÂ Â |
| UniProt Entry Name: | TENN_HUMAN |
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