TNK1 Polyclonal Antibody (CAB21300)
- SKU:
- CAB21300
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | TNK1 Polyclonal Antibody |
SKU: | CAB21300 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-380 of human TNK1 (NP_001238831.1). |
Sequence: | LPEP EGGL KCLI PEGA VCRG ELLG SGCF GVVH RGLW TLPS GKSV PVAV KSLR VGPE GPMG TELG DFLR EVSV MMNL EHPH VLRL HGLV LGQP LQMV MELA PLGS LHAR LTAP APTP PLLV ALLC LFLR QLAG AMAY LGAR GLVH RDLA TRNL LLAS PRTI KVAD FGLV RPLG GARG RYVM GGPR PIPY AWCA PESL RHGA FSSA SDVW MFGV TLWE MFSG GEEP WAGV PPYL ILQR LEDR ARLP RPPL CSRA LYSL ALRC WAPH PADR PSFS HLEG LLQE A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | KOS1; TNK1 |
Positive Sample: | T-47D |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 72kDa |
Observed MW: | 72kDa |
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8711 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |