The TNFRSF6B Polyclonal Antibody (CAB0649) is a valuable tool for research involving TNFRSF6B, a cell surface receptor also known as decoy receptor 3 (DcR3). This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to TNFRSF6B, this antibody enables accurate detection and analysis of the protein in various cell types, making it ideal for studies in immunology, cancer research, and other related fields.TNFRSF6B is involved in the regulation of immune responses and apoptosis, playing a crucial role in modulating inflammatory processes and cell survival. Its role as a decoy receptor for certain cytokines and apoptosis-inducing ligands gives it significant importance in diseases such as cancer, autoimmune disorders, and inflammatory conditions.
Research into TNFRSF6B can provide insights into these diseases and potentially lead to the development of targeted therapies that modulate immune responses and promote cell survival.Overall, the TNFRSF6B Polyclonal Antibody is a valuable tool for researchers studying TNFRSF6B and its implications in various diseases and immunological processes. Its high reactivity and specificity make it a reliable choice for Western blot applications, aiding in the accurate detection and analysis of TNFRSF6B protein levels in different cell types and conditions.
Product Name:
TNFRSF6B Rabbit Polyclonal Antibody
SKU:
CAB0649
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human TNFRSF6B (NP_003814.1).
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.
Purification Method:
Affinity purification
Gene ID:
8771
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TNFRSF6B antibody (CAB0649) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
