OX40 Rabbit Polyclonal Antibody (CAB7499)
- SKU:
- CAB7499
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | OX40 Rabbit Polyclonal Antibody |
SKU: | CAB7499 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-214 of human CD134/OX40 (NP_003318.1). |
Sequence: | LHCV GDTY PSND RCCH ECRP GNGM VSRC SRSQ NTVC RPCG PGFY NDVV SSKP CKPC TWCN LRSG SERK QLCT ATQD TVCR CRAG TQPL DSYK PGVD CAPC PPGH FSPG DNQA CKPW TNCT LAGK HTLQ PASN SSDA ICED RDPP ATQP QETQ GPPA RPIT VQPT EAWP RTSQ GPST RPVE VPGG RA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OX40; ACT35; CD134; IMD16; TXGP1L; CD134/OX40 |
Positive Sample: | HepG2,BT-474,SW620,MCF7,Mouse thymus,Mouse skeletal muscle,Mouse lung,Mouse intestine,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 29kDa |
Observed MW: | 37kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Purification Method: | Affinity purification |
Gene ID: | 7293 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |