OX40 Rabbit Polyclonal Antibody (CAB3646)
- SKU:
- CAB3646
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | OX40 Rabbit Polyclonal Antibody |
SKU: | CAB3646 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD134/OX40 (NP_003318.1). |
Sequence: | TATQ DTVC RCRA GTQP LDSY KPGV DCAP CPPG HFSP GDNQ ACKP WTNC TLAG KHTL QPAS NSSD AICE DRDP PATQ PQET QGPP ARPI TVQP TEAW PRTS Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OX40; ACT35; CD134; IMD16; TXGP1L; CD134/OX40 |
Positive Sample: | Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 29kDa |
Observed MW: | 48kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Purification Method: | Affinity purification |
Gene ID: | 7293 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |