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CD134 Polyclonal Antibody

SKU:
CAB24523
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

CD134 Polyclonal Antibody (CAB24523)

The CD134 Polyclonal Antibody is a crucial tool for researchers studying CD134, an essential cell surface molecule involved in immune regulation and activation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for Western blot applications. By binding to the CD134 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an invaluable resource for studies in immunology and cancer research.CD134, also known as OX40, is a co-stimulatory molecule that plays a pivotal role in regulating immune responses and promoting T-cell activation and survival.

Its involvement in modulating immune function makes it a key target for research in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the mechanisms by which CD134 operates is essential for developing novel therapies that manipulate immune responses in these disease contexts.Overall, the CD134 Polyclonal Antibody is a valuable asset for researchers seeking to unravel the complexities of immune regulation and develop targeted treatments for a range of immune-related diseases.

Product Name:CD134 Polyclonal Antibody
Product Code:CAB24523
Reactivity:Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:Rat spleen

Enables tumor necrosis factor-activated receptor activity. Involved in negative regulation of apoptotic process; positive regulation of B cell proliferation; and regulation of gene expression. Acts upstream of or within several processes, including cellular defense response; negative regulation of cytokine production; and regulation of protein kinase activity. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 16. Orthologous to human TNFRSF4 (TNF receptor superfamily member 4).

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-211 of mouse CD134 (NP_035789.1).
Sequence:VTARR LNCVK HTYPS GHKCC RECQP GHGMV SRCDH TRDTL CHPCE TGFYN EAVNY DTCKQ CTQCN HRSGS ELKQN CTPTQ DTVCR CRPGT QPRQD SGYKL GVDCV PCPPG HFSPG NNQAC KPWTN CTLSG KQTRH PASDS LDAVC EDRSL LATLL WETQR PTFRP TTVQS TTVWP RTSEL PSPPT LVTPE GP
Synonyms:Ox40, ACT35, CD134, Ly-70, Txgp1, TXGP1L
Calculated MW:30kDa
Observed MW:30kDa

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