TNFRSF21 Rabbit Polyclonal Antibody (CAB7365)
- SKU:
- CAB7365
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TNFRSF21 Rabbit Polyclonal Antibody |
SKU: | CAB7365 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 371-655 of human TNFRSF21 (NP_055267.1). |
Sequence: | RKSS RTLK KGPR QDPS AIVE KAGL KKSM TPTQ NREK WIYY CNGH GIDI LKLV AAQV GSQW KDIY QFLC NASE REVA AFSN GYTA DHER AYAA LQHW TIRG PEAS LAQL ISAL RQHR RNDV VEKI RGLM EDTT QLET DKLA LPMS PSPL SPSP IPSP NAKL ENSA LLTV EPSP QDKN KGFF VDES EPLL RCDS TSSG SSAL SRNG SFIT KEKK DTVL RQVR LDPC DLQP IFDD MLHF LNPE ELRV IEEI PQAE DKLD RLFE IIGV KSQE ASQT LLDS VYSH LPDL L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DR6; CD358; BM-018; TNFRSF21 |
Positive Sample: | HT-29,A-549,SW480,SW620,Mouse kidney,Mouse brain,Mouse lung,Rat brain,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 72kDa |
Observed MW: | 110kDa |
This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Purification Method: | Affinity purification |
Gene ID: | 27242 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |