GITR/TNFRSF18 Rabbit Polyclonal Antibody (CAB15625)
- SKU:
- CAB15625
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | GITR/TNFRSF18 Rabbit Polyclonal Antibody |
SKU: | CAB15625 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-255 of human GITR/TNFRSF18 (NP_683699.1). |
Sequence: | QRPT GGPG CGPG RLLL GTGT DARC CRVH TTRC CRDY PGEE CCSE WDCM CVQP EFHC GDPC CTTC RHHP CPPG QGVQ SQGK FSFG FQCI DCAS GTFS GGHE GHCK PWTD CCWR CRRR PKTP EAAS SPRK SGAS DRQR RRGG WETC GCEP GRPP GPPT AASP SPGA PQAA GALR SALG RALL PWQQ KWVQ EGGS DQRP GPCS SAAA AGPC RRER ETQS WPPS SLAG PDGV GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AITR; GITR; CD357; GITR-D; ENERGEN; GITR/TNFRSF18 |
Positive Sample: | Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | external side of plasma membrane, extracellular region, plasma membrane |
Calculated MW: | 26kDa |
Observed MW: | 30kDa |
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 8784 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |