The TNFRSF14 Polyclonal Antibody (CAB1969) is an essential tool for researchers studying TNFRSF14, a cell surface receptor known for its role in immune regulation and cell signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.TNFRSF14, also called HVEM (herpes virus entry mediator), is a key player in immune responses, particularly in regulating T cell activation and tolerance. Its involvement in immune system modulation makes it a valuable target for studies related to immunology, infectious diseases, and cancer research.
By detecting and analyzing TNFRSF14 protein expression in various cell types, researchers can gain critical insights into its function and potential therapeutic implications.Understanding the mechanisms and signaling pathways involving TNFRSF14 is crucial for advancing our knowledge of immune regulation and developing novel treatments for diseases associated with immune dysfunction. The TNFRSF14 Polyclonal Antibody is a reliable tool for investigating the intricate roles of TNFRSF14 in health and disease.
Product Name:
HVEM/TNFRSF14 Rabbit Polyclonal Antibody
SKU:
CAB1969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 39-202 of human HVEM/TNFRSF14 (NP_003811.2).
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8764
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Raji cells, using HVEM/TNFRSF14 antibody (CAB1969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
