The TNFRSF10D Polyclonal Antibody (CAB6136) is a valuable tool for researchers studying TNFRSF10D, a member of the tumor necrosis factor receptor superfamily involved in apoptosis and immune regulation. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in various applications, including Western blotting. By binding specifically to the TNFRSF10D protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for immunology and cancer research studies.
TNFRSF10D, also known as TRAIL-R4, is a key player in apoptosis pathways and immune system modulation, making it a promising target for investigation in diseases such as cancer and autoimmune disorders. Understanding the role of TNFRSF10D in regulating cell death and immune responses is critical for the development of novel therapeutic approaches that target these processes. The TNFRSF10D Polyclonal Antibody provides researchers with a reliable tool for advancing their studies in this important field.
Product Name:
TNFRSF10D Rabbit Polyclonal Antibody
SKU:
CAB6136
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 257-386 of human TNFRSF10D (NP_003831.2).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.
Purification Method:
Affinity purification
Gene ID:
8793
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from THP-1 cells, using TNFRSF10D Rabbit pAb (CAB6136) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
