TNFRSF10C Rabbit Polyclonal Antibody (CAB1137)
- SKU:
- CAB1137
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | TNFRSF10C Rabbit Polyclonal Antibody |
SKU: | CAB1137 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-238 of human TNFRSF10C (NP_003832.2). |
Sequence: | VEEF GANA TVET PAAE ETMN TSPG TPAP AAEE TMNT SPGT PAPA AEET MTTS PGTP APAA EETM TTSP GTPA PAAE ETMT TSPG TPAS S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR; TNFRSF10C |
Positive Sample: | Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Purification Method: | Affinity purification |
Gene ID: | 8794 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |