The TNFRSF10A Polyclonal Antibody (CAB6267) is a valuable tool for researchers studying TNFRSF10A, a member of the TNF receptor superfamily known for its role in apoptosis and immune regulation. This antibody, produced in rabbits, exhibits high specificity towards human TNFRSF10A and is validated for use in Western blotting applications.TNFRSF10A, also known as TRAIL receptor 1, is involved in regulating cell death pathways and modulating immune responses. Its ability to induce apoptosis in cancer cells has made TNFRSF10A a promising target for cancer therapy research.
Furthermore, its role in immune regulation suggests potential implications in autoimmune diseases and inflammatory conditions.By utilizing the TNFRSF10A Polyclonal Antibody, researchers can effectively detect and analyze TNFRSF10A protein expression in various cell types, providing valuable insights into its function in both normal and disease states. This antibody is a valuable tool for studies in oncology, immunology, and molecular biology, offering the opportunity to further understand the mechanisms underlying TNFRSF10A-mediated processes.
Product Name:
TNFRSF10A Rabbit Polyclonal Antibody
SKU:
CAB6267
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 269-468 of human TNFRSF10A (NP_003835.3).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Purification Method:
Affinity purification
Gene ID:
8797
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of DU145 cells, using TNFRSF10A antibody (CAB6267) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
