TNFAIP6 Rabbit Polyclonal Antibody (CAB6419)
- SKU:
- CAB6419
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TNFAIP6 Rabbit Polyclonal Antibody |
SKU: | CAB6419 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-277 of human TNFAIP6 (NP_009046.2). |
Sequence: | WGFK DGIF HNSI WLER AAGV YHRE ARSG KYKL TYAE AKAV CEFE GGHL ATYK QLEA ARKI GFHV CAAG WMAK GRVG YPIV KPGP NCGF GKTG IIDY GIRL NRSE RWDA YCYN PHAK ECGG VFTD PKQI FKSP GFPN EYED NQIC YWHI RLKY GQRI HLSF LDFD LEDD PGCL ADYV EIYD SYDD VHGF VGRY CGDE LPDD IIST GNVM TLKF LSDA SVTA GGFQ IKYV AMDP VSKS SQGK NTST TSTG NKNF LAGR FSHL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TSG6; TSG-6; TNFAIP6 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | extracellular region, extracellular space |
Calculated MW: | 31kDa |
Observed MW: | 40kDa |
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
Purification Method: | Affinity purification |
Gene ID: | 7130 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |