TNFAIP3 Rabbit Polyclonal Antibody (CAB2127)
- SKU:
- CAB2127
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | TNFAIP3 Rabbit Polyclonal Antibody |
SKU: | CAB2127 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-738 of human TNFAIP3 (NP_006281.1). |
Sequence: | DRTG TSKC RKAG CVYF GTPE NKGF CTLC FIEY RENK HFAA ASGK VSPT ASRF QNTI PCLG RECG TLGS TMFE GYCQ KCFI EAQN QRFH EAKR TEEQ LRSS QRRD VPRT TQST SRPK CARA SCKN ILAC RSEE LCME CQH |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | A20; AISBL; AIFBL1; OTUD7C; TNFA1P2; TNFAIP3 |
Positive Sample: | THP-1 treated by TPA and LPS,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lysosome, Nucleus. |
Calculated MW: | 90kDa |
Observed MW: | 90kDa |
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7128 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |