The TNFAIP2 Monoclonal Antibody (PACO17288) is a valuable tool for research involving TNFAIP2, a protein that plays a crucial role in the regulation of inflammatory responses. This antibody, developed using advanced monoclonal antibody technology, specifically targets TNFAIP2 in human samples and is suitable for use in various research applications, including Western blotting and immunohistochemistry.TNFAIP2, also known as TNF alpha-induced protein 2, is involved in mediating the response to inflammatory stimuli and is implicated in various cellular processes, including cell proliferation and apoptosis.
Research on TNFAIP2 is important for gaining insights into its role in inflammatory disorders, such as autoimmune diseases and cancer, and for the development of targeted therapies.With its high specificity and sensitivity, the TNFAIP2 Monoclonal Antibody (PACO17288) provides researchers with a reliable tool for studying TNFAIP2 expression and function in different biological contexts. Its applications in immunology and cancer research make it a valuable asset for investigations aimed at understanding the mechanisms of inflammation and developing novel therapeutic strategies.
Antibody Name:
TNFAIP2 Antibody (PACO17288)
Antibody SKU:
PACO17288
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Fusion protein of human TNFAIP2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17288(TNFAIP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor α (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid, in a cell line expressing a oncogenic version of the retinoic acid, receptor α fusion protein, which suggested that this gene may be a retinoic acid, target gene in acute promyelocytic leukemia.
Synonyms:
tumor necrosis factor, alpha-induced protein 2
UniProt Protein Function:
TNFAIP2: May play a role as a mediator of inflammation and angiogenesis. Belongs to the SEC6 family.
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]
