The TNFAIP2 Polyclonal Antibody (PAC017287) is a valuable tool for researchers studying TNFAIP2, a protein involved in the regulation of immune responses and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to TNFAIP2, this antibody enables accurate detection and analysis of the protein in various cell types, making it an ideal choice for studies in immunology and cancer research.TNFAIP2, also known as tumor necrosis factor alpha-induced protein 2, plays a crucial role in modulating immune responses and inflammatory processes.
Its involvement in these pathways makes TNFAIP2 a significant target for investigation in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. A deeper understanding of TNFAIP2 function is essential for the development of potential therapeutic interventions that target immune regulation in these disease contexts.Overall, the TNFAIP2 Polyclonal Antibody (PAC017287) offers researchers a reliable and specific tool for exploring the role of TNFAIP2 in immune regulation and inflammatory processes, with the potential for advancing our understanding of disease mechanisms and therapeutic strategies.
Antibody Name:
TNFAIP2 Antibody (PACO17287)
Antibody SKU:
PACO17287
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human TNFAIP2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17287(TNFAIP2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor α (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid, in a cell line expressing a oncogenic version of the retinoic acid, receptor α fusion protein, which suggested that this gene may be a retinoic acid, target gene in acute promyelocytic leukemia.
Synonyms:
tumor necrosis factor, alpha-induced protein 2
UniProt Protein Function:
TNFAIP2: May play a role as a mediator of inflammation and angiogenesis. Belongs to the SEC6 family.
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]
