The TNF RII (TNFRSF1B/CD120b) Polyclonal Antibody is a valuable tool for research involving the TNF receptor family member TNF RII. This cell surface receptor is involved in mediating the biological effects of tumor necrosis factor (TNF), a key cytokine in the immune response. The antibody is raised in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications.TNF RII plays a crucial role in regulating immune responses, inflammation, and cell death pathways. It is a target of interest in studies related to inflammatory diseases, autoimmune disorders, and cancer.
By detecting and analyzing TNF RII expression, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.With its high reactivity and specificity for TNF RII, this polyclonal antibody is a valuable tool for researchers in immunology, oncology, and inflammatory disease research. It enables the detection and analysis of TNF RII protein levels in various cell types, providing valuable data for understanding the role of this receptor in health and disease.
Product Name:
TNF RII/TNFRSF1B/CD120b Polyclonal Antibody
SKU:
CAB24513
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 23-258 of mouse TNF RII/TNFRSF1B/CD120b(NP_035740.2).
Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion; regulation of nervous system development; and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization; apoptotic signaling pathway; and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).
Purification Method:
Affinity purification
Gene ID:
21938
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from L929 cells using TNF RII/TNFRSF1B/CD120b Rabbit pAb(CAB24513) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
