TNF RII/TNFRSF1B/CD120b Polyclonal Antibody (CAB24513)
- SKU:
- CAB24513
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TNF RII/TNFRSF1B/CD120b Polyclonal Antibody |
| SKU: | CAB24513 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Mouse |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 23-258 of mouse TNF RII/TNFRSF1B/CD120b(NP_035740.2). |
| Sequence: | VPAQ VVLT PYKP EPGY ECQI SQEY YDRK AQMC CAKC PPGQ YVKH FCNK TSDT VCAD CEAS MYTQ VWNQ FRTC LSCS SSCT TDQV EIRA CTKQ QNRV CACE AGRY CALK THSG SCRQ CMRL SKCG PGFG VASS RAPN GNVL CKAC APGT FSDT TSST DVCR PHRI CSIL AIPG NAST DAVC APES PTLS AIPR TLYV SQPE PTRS QPLD QEPG PSQT PSIL TSLG STPI IEQS TKGG |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:1000 - 1:5000 |
| Synonyms: | p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2; TNF RII/TNFRSF1B/CD120b |
| Positive Sample: | L929 |
| Conjugate: | Unconjugated |
| Cellular Localization: | Secreted and Cell membrane |
| Calculated MW: | 50kDa |
| Observed MW: | 50kDa |
Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion; regulation of nervous system development; and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization; apoptotic signaling pathway; and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).
| Purification Method: | Affinity purification |
| Gene ID: | 21938 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from L929 cells using TNF RII/TNFRSF1B/CD120b Rabbit pAb(CAB24513) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s. |
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