TNF a Monoclonal Antibody [NYRhTNFa-E2] (CPAB0031)
- SKU:
- CPAB0031
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- NYRhTNFa-E2
- Applications:
- IP
- WB
- ELISA
Description
TNF a Monoclonal Antibody [NYRhTNFa-E2] (CPAB0031)
The TNF-alpha Polyclonal Antibody (CPAB0031) is a valuable tool for researchers studying the tumor necrosis factor-alpha (TNF-alpha) protein, a key player in the immune response. This antibody, generated in rabbits, is highly specific for TNF-alpha and is optimized for use in Western blot applications.TNF-alpha is a cytokine involved in the inflammatory response and has been implicated in various diseases, including autoimmune disorders, inflammatory conditions, and cancer. The TNF-alpha Polyclonal Antibody enables the detection and analysis of TNF-alpha in diverse cell types, providing crucial insights into its role in disease pathogenesis.
By using this antibody, researchers can advance their understanding of TNF-alpha's functions and explore potential therapeutic strategies targeting TNF-alpha for the treatment of inflammatory and autoimmune diseases. Its high specificity and sensitivity make it a reliable tool for scientists working in immunology, oncology, and drug discovery.
Product Name: | TNF a Antibody |
Product Sku: | CPAB0031 |
Size: | 500μg |
Host Species: | Mouse |
Immunogen: | r.Human TNF-a |
Clone: | NYRhTNFa-E2. |
Reactivity: | Human |
Applications: | Immuneprecipitation, Western Blot, ELISA |
Purification Method: | Ion exchange |
Isotype: | IgG1 |
Background: | Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. |
Synonyms: | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2. |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |