TMX1 Rabbit Polyclonal Antibody (CAB17219)
- SKU:
- CAB17219
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | TMX1 Rabbit Polyclonal Antibody |
SKU: | CAB17219 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-280 of human TMX1 (NP_110382.3). |
Sequence: | KRRR PQPY PYPS KKLL SESA QPLK KVEE EQEA DEED VSEE EAES KEGT NKDF PQNA IRQR SLGP SLAT DKS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TMX; TXNDC; PDIA11; TXNDC1; TMX1 |
Positive Sample: | 293T,LO2,HeLa,Jurkat |
Cellular Localization: | Endoplasmic reticulum membrane, Membrane, Single-pass type I membrane protein. |
Calculated MW: | 32kDa |
Observed MW: | 35kDa |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.
Purification Method: | Affinity purification |
Gene ID: | 81542 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |