The Tmtc1 Polyclonal Antibody (PAC037594) is a valuable tool for researchers studying the Tmtc1 protein, a critical component involved in protein glycosylation and membrane trafficking processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the Tmtc1 protein, this antibody allows for the detection and analysis of Tmtc1 in various cell types, making it an essential tool for studies in cell biology and molecular biology research.Tmtc1 is known to play a key role in the quality control of glycoproteins and the regulation of protein transport within cells.
Dysfunction or dysregulation of Tmtc1 has been linked to various diseases, including neurological disorders and metabolic syndromes. As such, understanding the function and regulation of Tmtc1 is crucial for identifying potential therapeutic targets and developing treatments for these conditions.In summary, the Tmtc1 Polyclonal Antibody is a reliable reagent for researchers investigating the role of Tmtc1 in cellular processes and disease pathways. Its specificity and sensitivity make it a valuable asset for studies aimed at unraveling the complex mechanisms associated with Tmtc1 function.
Western blot. All lanes: TMTC1 antibody at 6µg/ml + Mouse large intestine tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 99, 88, 74, 66, 26 kDa. Observed band size: 99 kDa.
Immunofluorescent analysis of HepG2 cells using PACO37594 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
Transmembrane and TPR repeat-containing protein 1, TMTC1
UniProt Protein Function:
TMTC1: Belongs to the TMTC family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 12p11.22Cellular Component: integral to membrane; mitochondrionBiological Process: RNA processing