The TMEM79 Polyclonal Antibody (PAC059916) is a vital tool for researchers studying TMEM79, a transmembrane protein that plays a key role in skin barrier function and immune responses. This antibody, produced in rabbits, exhibits high specificity for human samples and is ideal for use in various applications, including Western blotting.TMEM79, also known as the transmembrane protein 79, is involved in the regulation of skin barrier function and the immune response to pathogens. Its role in maintaining skin integrity and regulating immune responses makes it a promising target for research in dermatology, immunology, and skin diseases. By utilizing the TMEM79 Polyclonal Antibody, researchers can effectively detect and analyze TMEM79 expression in different cell types, facilitating the investigation of its function in various physiological and pathological conditions.
Understanding the molecular mechanisms underlying TMEM79 expression and function is crucial for developing potential treatments for skin disorders, immune-related diseases, and inflammatory conditions. The TMEM79 Polyclonal Antibody is a valuable tool for researchers investigating the role of TMEM79 in skin biology and immune regulation, offering reliable and specific detection of this important transmembrane protein.
Antibody Name:
TMEM79 Antibody (PACO59916)
Antibody SKU:
PACO59916
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Transmembrane protein 79 protein (13-127AA)
IHC image of PACO59916 diluted at 1:300 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation (By similarity).
Synonyms:
Transmembrane protein 79 (Mattrin), TMEM79, MATT
UniProt Protein Function:
TMEM79: Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formationProtein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1q22Cellular Component: lysosomal membrane; trans-Golgi network membraneMolecular Function: protein bindingBiological Process: epithelial cell maturation; positive regulation of epidermis development; regulated secretory pathway
