The TMEM67 Polyclonal Antibody (CAB15549) is a vital tool for researchers studying TMEM67, a transmembrane protein associated with various cellular functions. This antibody, produced through immunization of rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications.TMEM67 is a crucial molecule involved in cellular processes such as cell adhesion, migration, and signaling. Its diverse functions make it a key player in developmental biology, particularly in organogenesis and tissue formation. By targeting TMEM67 with this antibody, researchers can effectively detect and analyze its expression in a variety of cell types, offering insights into its roles in development, disease, and cellular physiology.
With TMEM67 being implicated in conditions like ciliopathies and developmental disorders, this antibody serves as a valuable tool for investigating the molecular mechanisms underlying these conditions. By elucidating the functions and interactions of TMEM67, researchers can pave the way for potential therapeutic interventions targeting this protein in disease settings.
Product Name:
TMEM67 Rabbit Polyclonal Antibody
SKU:
CAB15549
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 780-940 of human TMEM67 (NP_714915.3).
The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).
Purification Method:
Affinity purification
Gene ID:
91147
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TMEM67 Rabbit pAb (CAB15549) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
