The TMEM55A Polyclonal Antibody (CAB15471) is a valuable tool for researchers studying TMEM55A, a protein involved in intracellular membrane dynamics and lipid metabolism. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to the TMEM55A protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and lipid metabolism research.TMEM55A plays a crucial role in cellular functions such as vesicular trafficking, membrane organization, and lipid metabolism.
Its involvement in these processes suggests its potential impact on disease states such as metabolic disorders, neurodegenerative diseases, and cancer. By studying the function of TMEM55A, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets for intervention.Overall, the TMEM55A Polyclonal Antibody offers a reliable tool for exploring the roles of TMEM55A in cellular processes and disease pathogenesis, providing valuable information for advancing our understanding of health and disease.
Product Name:
TMEM55A Rabbit Polyclonal Antibody
SKU:
CAB15471
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-195 of human TMEM55A (NP_061180.1).
Sequence:
VMLI SEEQ PAQP ALPI QPEG TRVV CGHC GNTF LWME LRFN TLAK CPHC KKIS SVGS ALPR RRCC AY
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:200 - 1:2000
Synonyms:
TMEM55A
Positive Sample:
Mouse liver
Conjugate:
Unconjugated
Cellular Localization:
Late endosome membrane, Lysosome membrane, Multi-pass membrane protein.
Calculated MW:
28kDa
Observed MW:
28kDa
TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).
Purification Method:
Affinity purification
Gene ID:
55529
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using TMEM55A Rabbit pAb (CAB15471) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
