The TMEM43 Polyclonal Antibody (CAB8509) is a highly specific tool for researchers studying TMEM43, a transmembrane protein involved in various cellular processes. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in applications such as Western blotting.TMEM43, also known as transmembrane protein 43, plays a key role in cellular functions related to membrane dynamics and organelle organization. Its involvement in these processes makes it a potential target for research in cell biology, molecular biology, and related fields. By targeting the TMEM43 protein, this antibody facilitates the detection and analysis of TMEM43 expression in diverse cell types, allowing for further investigation into its function and potential implications in disease.
Researchers interested in unraveling the role of TMEM43 in cellular pathways and disease mechanisms will find the TMEM43 Polyclonal Antibody (CAB8509) to be a valuable tool for their studies. Its specificity, reactivity, and reliability make it an essential component for investigations aimed at elucidating the functions and significance of TMEM43 in various biological contexts.
Product Name:
TMEM43 Rabbit Polyclonal Antibody
SKU:
CAB8509
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-310 of human TMEM43 (NP_077310.1).
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
Purification Method:
Affinity purification
Gene ID:
79188
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TMEM43 antibody (CAB8509) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
