The TMEM30B Polyclonal Antibody (PACO22024) is a valuable tool for researchers studying TMEM30B, a transmembrane protein known to play a role in lipid transport and metabolism. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to the TMEM30B protein, researchers can easily detect and analyze its expression in various cell types, making it ideal for studies in lipid biology and metabolic research.TMEM30B is a key player in lipid homeostasis and has been implicated in various metabolic diseases, making it a promising target for therapeutic intervention.
By understanding the function and regulation of TMEM30B, researchers can uncover new insights into lipid metabolism and potentially identify novel treatment strategies for conditions such as obesity, cardiovascular disease, and metabolic disorders.Overall, the TMEM30B Polyclonal Antibody (PACO22024) is a reliable tool for researchers looking to delve deeper into the role of TMEM30B in lipid biology and metabolic diseases, paving the way for new advancements in the field of lipid metabolism research.
Antibody Name:
TMEM30B Antibody (PACO22024)
Antibody SKU:
PACO22024
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human TMEM30B.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using TMEM30B antibody.
Background:
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate Probable. Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
Synonyms:
Cell cycle control protein 50B; Transmembrane protein 30B; TMEM30B; CDC50B; CC50B
UniProt Protein Function:
TMEM30B: Belongs to the CDC50/LEM3 family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 14q23.1Cellular Component: integral to membrane; plasma membraneMolecular Function: protein bindingBiological Process: lipid transport
