The TMEM176B Polyclonal Antibody (CAB16118) is a crucial tool for researchers studying TMEM176B, a transmembrane protein that plays a role in immune regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TMEM176B protein, this antibody enables the detection and analysis of TMEM176B in various cell types, making it an essential tool for research in immunology and cancer studies.TMEM176B is known for its involvement in immune response modulation, making it a promising target for investigating diseases such as cancer, autoimmune conditions, and chronic inflammatory disorders.
By understanding the function of TMEM176B, researchers can develop potential therapies that aim to manipulate or enhance immune responses in these disease settings. The TMEM176B Polyclonal Antibody is therefore a valuable resource for scientists aiming to unravel the role of this protein in immune regulation and disease pathogenesis.
Product Name:
TMEM176B Rabbit Polyclonal Antibody
SKU:
CAB16118
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 148-208 of human TMEM176B (NP_054739.3).
Sequence:
NSFI WQTE PFLY IDTV CDRS DPVF PTTG YRWM RRSQ ENQW QKEE CRAY MQML RKLF TAIR A
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
LR8; MS4B2; TMEM176B
Positive Sample:
U-87MG,Mouse lung,Mouse liver
Conjugate:
Unconjugated
Cellular Localization:
Multi-pass membrane protein, Nucleus membrane
Calculated MW:
29kDa
Observed MW:
29kDa
Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be located in nuclear membrane. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
28959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TMEM176B Rabbit pAb (CAB16118) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
