Description
TMEM174 Antibody (PACO30510)
The TMEM174 Polyclonal Antibody (PAC030510) is a vital research tool for investigating TMEM174, a protein involved in immune responses and cell signaling pathways. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot experiments. By binding to the TMEM174 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for studies in immunology and cancer research.
TMEM174, also known as immune response regulator, plays a crucial role in maintaining immune system balance by modulating immune cell activation and cytokine production. Its involvement in immune regulation makes it a promising target for research related to cancer, autoimmune diseases, and inflammatory disorders. Understanding the function of TMEM174 is essential for developing therapeutic strategies that manipulate immune responses in these pathological conditions.
Antibody Name: | TMEM174 Antibody (PACO30510) |
Antibody SKU: | PACO30510 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Transmembrane protein 174 protein (94-243AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: TMEM174 antibody at 0.8µg/ml + Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 27, 24 kDa Observed band size: 27 kDa . |
![]() | Immunofluorescent analysis of 293T cells using PACO30510 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO30510 at dilution of 1:100. |
Synonyms: | Transmembrane protein 174, TMEM174 |
UniProt Protein Function: | TMEM174: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 5q13.2Cellular Component: endoplasmic reticulum membrane; integral to membrane |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8WUU8 |
NCBI GenInfo Identifier: | 23397475 |
NCBI Gene ID: | 134288 |
NCBI Accession: | NP_694949.1 |
UniProt Secondary Accession: | Q8WUU8,Q96N81, B2RDA0 |
UniProt Related Accession: | Q8WUU8 |
Molecular Weight: | 26,287 Da |
NCBI Full Name: | transmembrane protein 174 |
NCBI Synonym Full Names: | transmembrane protein 174 |
NCBI Official Symbol: | TMEM174Â Â |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | transmembrane protein 174 |
UniProt Protein Name: | Transmembrane protein 174 |
UniProt Synonym Protein Names: | |
Protein Family: | Transmembrane protein |
UniProt Gene Name: | TMEM174Â Â |
UniProt Entry Name: | TM174_HUMAN |