The TMEM131L Polyclonal Antibody (PAC063663) is a key tool for researchers studying TMEM131L, a transmembrane protein associated with cell signaling and membrane processes. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting TMEM131L in human samples, making it ideal for use in Western blot procedures.TMEM131L is known for its role in cellular communication and membrane function, making it a target of interest in various research areas such as signal transduction and cell biology. By targeting the TMEM131L protein, this antibody enables researchers to accurately detect and analyze its presence in different cell types, facilitating in-depth investigations into its functions and interactions.
With its potential implications in cell signaling pathways and membrane dynamics, TMEM131L represents a promising target for studies related to cancer biology, developmental biology, and molecular pharmacology. By utilizing this antibody in their experiments, researchers can gain valuable insights into the role of TMEM131L in cellular processes and pave the way for novel discoveries in these fields.
Antibody Name:
TMEM131L Antibody (PACO63663)
Antibody SKU:
PACO63663
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Transmembrane protein 131-like protein (963-978AA)
Immunofluorescence staining of U251 cells with PACO63663 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation.
Synonyms:
Transmembrane protein 131-like, TMEM131L, KIAA0922
