The TMEM109 Polyclonal Antibody (PACO31776) is a valuable tool for researchers studying TMEM109, a transmembrane protein that plays a role in various cellular functions. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TMEM109 protein, this antibody allows for the detection and analysis of TMEM109 in different cell types, making it an ideal choice for studies in cell biology and molecular biology research.
TMEM109 is known to be involved in processes such as cell proliferation, migration, and invasion, making it a potential target for understanding diseases like cancer and developmental disorders. By studying TMEM109 and its functions, researchers can gain insights into the mechanisms underlying these conditions and identify potential therapeutic targets. The TMEM109 Polyclonal Antibody is a valuable tool for investigating the role of TMEM109 in various biological processes and diseases.
Immunohistochemistry of paraffin-embedded human melanoma using PACO31776 at dilution of 1:100.
Immunofluorescent analysis of MCF-7 cells using PACO31776 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro (By similarity).
Synonyms:
Transmembrane protein 109 (Mitsugumin-23) (Mg23), TMEM109
UniProt Protein Function:
TMEM109: Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q12.2Cellular Component: nuclear outer membrane; sarcoplasmic reticulum membrane; integral to membraneBiological Process: DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
