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TMEFF2 Monoclonal Antibody [PJ4B6AT] (CPAB0559)

SKU:
CPAB0559
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PJ4B6AT
Applications:
WB
ELISA
IHC
€149
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Description

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TMEFF2 Monoclonal Antibody [PJ4B6AT] (CPAB0559)

The TMEFF2 Polyclonal Antibody (CPAB0559) is a valuable tool for researchers studying TMEFF2, a transmembrane protein known for its role in various cellular processes, including cell proliferation and migration. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the TMEFF2 protein, this antibody allows for the detection and analysis of TMEFF2 expression in a variety of cell types, making it ideal for studies in cancer biology and neuroscience.

TMEFF2, also known as tomoregulin-2, is a promising target for research into cancer progression and neural development. Its involvement in regulating cell growth and migration suggests its potential as a biomarker or therapeutic target in cancer and neurodegenerative disorders. By investigating the functions of TMEFF2, researchers can gain valuable insights into disease mechanisms and potentially identify new strategies for treatment.

Product Name:TMEFF2 Antibody
Product Sku:CPAB0559
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TMEFF2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TMEFF2 amino acids 41-15 purified from Ecoli.
Clone:PJ4B6AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:TMEFF2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:TMEFF2 is a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor€“like domain. TMEFF2 has limited normal tissue distribution and is highly overexpressed in prostate cancer. The shedded form of TMEFF2 up-regulates cancer cell proliferation, most likely by promoting ERK1/2 phosphorylation. TMEFF2 is down-regulated in tumor cell lines in response to a high level of methylation in the 5'' region.
Synonyms:TMEFF2, Tomoregulin-2, Transmembrane protein with EGF-like and two follistatin-like domains, Hyperplastic polyposis protein 1, HPP1, TENB2, TPEF, TR, CT120.2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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