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TMED4 Antibody (PACO12789)

SKU:
PACO12789
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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TMED4 Antibody (PACO12789)

The TMED4 antibody (PACO12789) is a high-quality polyclonal antibody designed for research involving TMED4, a protein involved in intracellular trafficking and protein transport. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting, immunofluorescence, and immunohistochemistry.TMED4, also known as Transmembrane Emp24 Protein Transport Domain Containing 4, plays a critical role in the Golgi apparatus and endoplasmic reticulum, where it facilitates the transport of proteins to their proper cellular destinations.

Dysfunction of TMED4 has been implicated in various diseases, including neurodegenerative disorders and cancer, making it a valuable target for research in these areas.With the ability to detect and analyze TMED4 protein in different cell types, this antibody is ideal for studies in cell biology, molecular biology, and cancer research. By understanding the function and regulation of TMED4, researchers can gain insights into cellular processes and potentially identify new therapeutic targets for the treatment of diseases associated with protein trafficking abnormalities.

Antibody Name:TMED4 Antibody (PACO12789)
Antibody SKU:PACO12789
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human TMED4
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:transmembrane emp24 protein transport domain containing 4;TMED4;ERS25;HNLF ;
UniProt Protein Function:TMED4: Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis. Belongs to the EMP24/GP25L family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 7p13

Molecular Function:signal transducer activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade

UniProt Code:Q7Z7H5
NCBI GenInfo Identifier:62287892
NCBI Gene ID:222068
NCBI Accession:Q7Z7H5.1
UniProt Secondary Accession:Q7Z7H5,Q56VW3, Q7Z432, Q8N2P6, A4D2K8, B4DFJ4,
UniProt Related Accession:Q7Z7H5
Molecular Weight:20,781 Da
NCBI Full Name:Transmembrane emp24 domain-containing protein 4
NCBI Synonym Full Names:transmembrane p24 trafficking protein 4
NCBI Official Symbol:TMED4  
NCBI Official Synonym Symbols:HNLF; ERS25; p24a3; GMP25iso; p24alpha3  
NCBI Protein Information:transmembrane emp24 domain-containing protein 4
UniProt Protein Name:Transmembrane emp24 domain-containing protein 4
UniProt Synonym Protein Names:Endoplasmic reticulum stress-response protein 25; ERS25; GMP25iso; Putative NF-kappa-B-activating protein 156; p24 family protein alpha-3; p24alpha3
Protein Family:Transmembrane emp24 domain-containing protein
UniProt Gene Name:TMED4  
UniProt Entry Name:TMED4_HUMAN

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