The TMC5 Polyclonal Antibody (CAB16144) is a vital tool for researchers studying TMC5, a transmembrane protein involved in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the TMC5 protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for investigations in molecular biology and cell biology.TMC5 is known for its role in ion transport and calcium signaling within cells, making it a potential target for understanding diseases related to these pathways, such as neurological disorders and certain cancers.
By studying the function of TMC5, researchers can gain insight into its impact on cellular physiology and its potential as a therapeutic target in diseases linked to ion channels and calcium regulation.Overall, the TMC5 Polyclonal Antibody is a valuable resource for researchers seeking to unravel the cellular mechanisms involving TMC5 and its implications in various diseases, paving the way for potential therapeutic advancements in the future.
Product Name:
TMC5 Rabbit Polyclonal Antibody
SKU:
CAB16144
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 676-760 of human TMC5 (NP_079056.2).
Sequence:
YWQI TEGR KIMI RLLH EQII NEGK DKMF LIEK LIKL QDME KKAN PSSL VLER REVE QQGF LHLG EHDG SLDL RSRR SVQE GNPR A
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
TMC5
Positive Sample:
BT-474
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein
Calculated MW:
115kDa
Observed MW:
114kDa
Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Located in extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
79838
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from BT-474 cells, using TMC5 Rabbit pAb (CAB16144) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
