UniProt Protein Function: | TMBIM4: Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release. Belongs to the BI1 family. LFG subfamily.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 12q14.3Cellular Component: Golgi membrane; Golgi stack; integral to membraneMolecular Function: protein bindingBiological Process: apoptosis; negative regulation of apoptosis; regulation of calcium-mediated signaling |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9HC24 |
NCBI GenInfo Identifier: | 322510100 |
NCBI Gene ID: | 51643 |
NCBI Accession: | Q9HC24.3 |
UniProt Secondary Accession: | Q9HC24,Q542Z6, Q9UHY5, Q9Y3C2 |
UniProt Related Accession: | Q9HC24 |
Molecular Weight: | 26,971 Da |
NCBI Full Name: | Protein lifeguard 4 |
NCBI Synonym Full Names: | transmembrane BAX inhibitor motif containing 4 |
NCBI Official Symbol: | TMBIM4Â Â |
NCBI Official Synonym Symbols: | S1R; GAAP; LFG4; ZPRO; CGI-119Â Â |
NCBI Protein Information: | protein lifeguard 4 |
UniProt Protein Name: | Protein lifeguard 4 |
UniProt Synonym Protein Names: | Golgi anti-apoptotic protein; Protein S1R; Transmembrane BAX inhibitor motif-containing protein 4; Z-protein |
Protein Family: | Protein lifeguard |
UniProt Gene Name: | TMBIM4Â Â |
UniProt Entry Name: | LFG4_HUMAN |