The TM7SF2 Polyclonal Antibody (CAB17541) is a valuable tool for researchers studying TM7SF2, a transmembrane protein involved in cholesterol metabolism and cellular lipid homeostasis. This rabbit-derived antibody is highly specific for TM7SF2 and has been validated for use in Western blot applications. It recognizes the TM7SF2 protein with high sensitivity, allowing for accurate detection and analysis in various cell types.TM7SF2 is a key player in lipid metabolism, playing a role in cholesterol synthesis and regulation.
Dysregulation of TM7SF2 has been implicated in various metabolic disorders, making it a promising target for research in the fields of cardiovascular diseases, obesity, and diabetes. By studying the function and expression of TM7SF2, researchers can gain valuable insights into the mechanisms of lipid metabolism and potential therapeutic approaches for related conditions.
Product Name:
TM7SF2 Rabbit Polyclonal Antibody
SKU:
CAB17541
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-250 of human TM7SF2 (NP_003264.2).
Enables delta14-sterol reductase activity. Involved in cholesterol biosynthetic process. Located in endoplasmic reticulum. Part of receptor complex.
Purification Method:
Affinity purification
Gene ID:
7108
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse uterus, using TM7SF2 Rabbit pAb (CAB17541) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.