TM4SF1 Antibody (PACO20646)
- SKU:
- PACO20646
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
TM4SF1 Antibody (PACO20646)
The TM4SF1 Polyclonal Antibody (PAC020646) is a valuable tool for researchers studying TM4SF1, a transmembrane protein involved in various cellular processes, including cell adhesion and migration. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the TM4SF1 protein, this antibody enables researchers to detect and analyze TM4SF1 expression in different cell types, making it a versatile tool for studies in cell biology and cancer research.
TM4SF1, also known as transmembrane 4 L six family member 1, plays a crucial role in cell signaling pathways that regulate cell proliferation, differentiation, and metastasis. Its involvement in these processes makes it a promising target for research aimed at understanding the mechanisms underlying cancer development and progression. By investigating the function of TM4SF1, researchers can gain insights into potential therapeutic strategies for treating cancer and other diseases characterized by abnormal cell growth and migration.
| Antibody Name: | TM4SF1 Antibody (PACO20646) |
| Antibody SKU: | PACO20646 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human TM4SF1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20646(TM4SF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20646(TM4SF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. |
| Synonyms: | transmembrane 4 L six family member 1 |
| UniProt Protein Function: | TM4SF1: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular. Present in high molecular weight complexes in tumor cells.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 3q21-q25Cellular Component: integral to plasma membrane |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30408 |
| NCBI GenInfo Identifier: | 267068 |
| NCBI Gene ID: | 4071 |
| NCBI Accession: | P30408.1 |
| UniProt Secondary Accession: | P30408,Q6IB51 |
| UniProt Related Accession: | P30408 |
| Molecular Weight: | 21,632 Da |
| NCBI Full Name: | Transmembrane 4 L6 family member 1 |
| NCBI Synonym Full Names: | transmembrane 4 L six family member 1 |
| NCBI Official Symbol: | TM4SF1Â Â |
| NCBI Official Synonym Symbols: | L6; H-L6; M3S1; TAAL6Â Â |
| NCBI Protein Information: | transmembrane 4 L6 family member 1 |
| UniProt Protein Name: | Transmembrane 4 L6 family member 1 |
| UniProt Synonym Protein Names: | Membrane component chromosome 3 surface marker 1; Tumor-associated antigen L6 |
| Protein Family: | Transmembrane 4 L6 family |
| UniProt Gene Name: | TM4SF1Â Â |
| UniProt Entry Name: | T4S1_HUMAN |
| Antibodies |
| TM4SF1 Antibody (PACO04259) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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