The TM2D3 Polyclonal Antibody (PAC040474) is a valuable tool for research involving TM2D3, a transmembrane protein known to play a role in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in applications such as Western blotting. By binding to the TM2D3 protein, researchers can easily detect and analyze its expression in different cell types, making it suitable for studies in cell biology and molecular biology.
TM2D3 is a protein with diverse functions, including involvement in cell proliferation, apoptosis, and signal transduction pathways. Its role in cellular processes makes it an interesting target for research in areas such as cancer biology, neurobiology, and developmental biology. Investigating the function of TM2D3 can provide valuable insights into the mechanisms underlying these biological processes and could potentially lead to the development of novel therapeutic strategies.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO40474 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO40474 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
TM2 domain-containing protein 3 (Beta-amyloid-binding protein-like protein 2) (BBP-like protein 2), TM2D3, BLP2
UniProt Protein Function:
TM2D3: contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. Several alternatively spliced transcript variants of this gene are described but the full length nature of some variants has not been determined. Multiple polyadenylation sites have been found in this gene. [provided by RefSeq, Jul 2008]Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 15q26.3
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. Several alternatively spliced transcript variants of this gene are described but the full length nature of some variants has not been determined. Multiple polyadenylation sites have been found in this gene. [provided by RefSeq, Jul 2008]
