TLR9 Rabbit Polyclonal Antibody (CAB14642)
- SKU:
- CAB14642
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TLR9 Rabbit Polyclonal Antibody |
SKU: | CAB14642 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 414-543 of human TLR9 (NP_059138.1). |
Sequence: | FPGL RYVD LSDN RISG ASEL TATM GEAD GGEK VWLQ PGDL APAP VDTP SSED FRPN CSTL NFTL DLSR NNLV TVQP EMFA QLSH LQCL RLSH NCIS QAVN GSQF LPLT GLQV LDLS HNKL DLYH EHSF TE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CD289; TLR9 |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic vesicle, Endoplasmic reticulum membrane, Endosome, Lysosome, Single-pass type I membrane protein, phagosome. |
Calculated MW: | 116kDa |
Observed MW: | 135kDa |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Purification Method: | Affinity purification |
Gene ID: | 54106 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |