TLR8 Rabbit Polyclonal Antibody (CAB1489)
- SKU:
- CAB1489
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TLR8 Rabbit Polyclonal Antibody |
SKU: | CAB1489 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 849-1041 of human TLR8 (NP_619542.1). |
Sequence: | HHLF YWDV WFIY NVCL AKVK GYRS LSTS QTFY DAYI SYDT KDAS VTDW VINE LRYH LEES RDKN VLLC LEER DWDP GLAI IDNL MQSI NQSK KTVF VLTK KYAK SWNF KTAF YLAL QRLM DENM DVII FILL EPVL QHSQ YLRL RQRI CKSS ILQW PDNP KAEG LFWQ TLRN VVLT ENDS RYNN MYVD SIKQ Y |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CD288; IMD98; hTLR8; TLR8 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 120kDa |
Observed MW: | 150kDa |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Purification Method: | Affinity purification |
Gene ID: | 51311 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |