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TLR7 Monoclonal Antibody [P4F4AT] (CPAB0549)

SKU:
CPAB0549
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
P4F4AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

TLR7 Monoclonal Antibody [P4F4AT] (CPAB0549)

The TLR7 Polyclonal Antibody (CPAB0549) is an essential tool for researchers studying Toll-like Receptor 7 (TLR7), a key player in the innate immune system's recognition of viral infections. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human TLR7, making it an invaluable reagent for Western blot applications.TLR7 is a pattern recognition receptor that senses single-stranded RNA from viruses and triggers immune responses to combat viral infections. Dysregulation of TLR7 signaling has been implicated in various autoimmune diseases and inflammatory conditions.

By targeting TLR7 with this antibody, researchers can investigate its role in immune responses and potentially develop new therapies for diseases such as lupus, arthritis, and viral infections.With its ability to specifically detect TLR7 protein expression in various cell types, the TLR7 Polyclonal Antibody is a valuable tool for advancing our understanding of immune responses and developing targeted treatments for immune-related disorders.

Product Name:TLR7 Antibody
Product Sku:CPAB0549
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TLR7 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TLR7 amino acids 451-5 purified from Ecoli.
Clone:P4F4AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:TLR7 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:TLR7 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR7 is principally expressed in lung, placenta, and spleen, and lies in close proximity to TLR8, on chromosome X.
Synonyms:Toll-like receptor 7, TLR7.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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