TLR6 Rabbit Polyclonal Antibody (CAB8185)
- SKU:
- CAB8185
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Description
Product Name: | TLR6 Rabbit Polyclonal Antibody |
SKU: | CAB8185 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 697-796 of human TLR6 (NP_006059.2). |
Sequence: | KSIF VLSP NFVQ SEWC HYEL YFAH HNLF HEGS NNLI LILL EPIP QNSI PNKY HKLK ALMT QRTY LQWP KEKS KRGL FWAN IRAA FNMK LTLV TENN DVKS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CD286; TLR6 |
Positive Sample: | K-562,Raji,RAW264.7,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic vesicle, Single-pass type I membrane protein, phagosome membrane. |
Calculated MW: | 92kDa |
Observed MW: | 100kDa |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
Purification Method: | Affinity purification |
Gene ID: | 10333 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |