TLR5 Rabbit Monoclonal Antibody (CAB8765)
- SKU:
- CAB8765
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TLR5 Rabbit Monoclonal Antibody |
SKU: | CAB8765 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-404 of human TLR5 (O60602). |
Sequence: | LILA HHIM GAGF GFHN IKDP DQNT FAGL ARSS VRHL DLSH GFVF SLNS RVFE TLKD LKVL NLAY NKIN KIAD EAFY GLDN LQVL NLSY NLLG ELYS SNFY GLPK VAYI DLQK NHIA IIQD QTFK FLEK LQTL DLRD NALT TIHF IPS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SLE1; TIL3; SLEB1; MELIOS; TLR5 |
Positive Sample: | HeLa,A549,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 98kDa |
Observed MW: | 105kDa |
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Purification Method: | Affinity purification |
Gene ID: | 7100 |
Clone Number: | ARC1294 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |