TLR5 Rabbit Polyclonal Antibody (CAB1721)
- SKU:
- CAB1721
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TLR5 Rabbit Polyclonal Antibody |
SKU: | CAB1721 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 714-858 of human TLR5 (NP_003259.2). |
Sequence: | HLDT QYSD QNRF NLCF EERD FVPG ENRI ANIQ DAIW NSRK IVCL VSRH FLRD GWCL EAFS YAQG RCLS DLNS ALIM VVVG SLSQ YQLM KHQS IRGF VQKQ QYLR WPED LQDV GWFL HKLS QQIL KKEK EKKK DNNI PLQT VATI S |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SLE1; TIL3; SLEB1; MELIOS; TLR5 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 98kDa |
Observed MW: | 100kDa |
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Purification Method: | Affinity purification |
Gene ID: | 7100 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |