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TLR2 Monoclonal Antibody [P1F10AT] (CPAB0551)

SKU:
CPAB0551
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
P1F10AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

TLR2 Monoclonal Antibody [P1F10AT] (CPAB0551)

The TLR2 Polyclonal Antibody (CPAB0551) is a valuable tool for researchers studying toll-like receptor 2 (TLR2), an important receptor involved in the recognition of microbial pathogens and activation of the innate immune response. This antibody, raised in rabbits, is highly specific for TLR2 and has been validated for use in various applications, including Western blotting and immunohistochemistry.TLR2 plays a crucial role in recognizing a wide range of microbial components, including bacteria, viruses, and fungi, and initiating the immune response against these pathogens. Dysregulation of TLR2 signaling has been implicated in various diseases, including infectious diseases, inflammatory disorders, and cancer.

Understanding the mechanisms underlying TLR2 activation and signaling is essential for developing novel therapeutic strategies targeting the immune response.The TLR2 Polyclonal Antibody (CPAB0551) allows for the detection and analysis of TLR2 expression in cells and tissues, making it a valuable tool for researchers investigating the role of TLR2 in immune responses, inflammation, and disease pathology. Its high specificity and sensitivity make it an ideal choice for studies in immunology, infectious diseases, and cancer research.

Product Name:TLR2 Antibody
Product Sku:CPAB0551
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TLR2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TLR2 amino acids 221-384 purified from Ecoli.
Clone:P1F10AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:TLR2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:TLR2 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Synonyms:Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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