TLR1 Rabbit Polyclonal Antibody (CAB0997)
- SKU:
- CAB0997
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | TLR1 Rabbit Polyclonal Antibody |
SKU: | CAB0997 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human TLR1 (NP_003254.2). |
Sequence: | DRSK NGLI HVPK DLSQ KTTI LNIS QNYI SELW TSDI LSLS KLRI LIIS HNRI QYLD ISVF KFNQ ELEY LDLS HNKL VKIS CHPT VNLK HLDL SFNA FDAL PICK EFGN MSQL KFLG LSTT HLEK SSVL PIAH LNIS KVLL VLGE TYGE KEDP EGLQ DFNT ESLH IVFP TNKE FHFI LDVS VKTV ANLE LSNI KCVL EDNK CSYF LSIL AKLQ TNPK LSNL TLNN IETT WNSF IRIL QLVW HTTV WYFS ISNV KLQG QLDF R |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | TIL; CD281; rsc786; TIL. LPRS5; TLR1 |
Positive Sample: | Mouse large intestine,Rat large intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic vesicle, Single-pass type I membrane protein, phagosome membrane. |
Calculated MW: | 90kDa |
Observed MW: | 90kDa |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7096 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |