TLN1 Rabbit Polyclonal Antibody (CAB4158)
- SKU:
- CAB4158
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | TLN1 Rabbit Polyclonal Antibody |
SKU: | CAB4158 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TLN1 (NP_006280.3). |
Sequence: | MVAL SLKI SIGN VVKT MQFE PSTM VYDA CRII RERI PEAP AGPP SDFG LFLS DDDP KKGI WLEA GKAL DYYM LRNG DTME YRKK QRPL KIRM LDGT VKTI MVDD SKTV TDML MTIC ARIG ITNH DEYS LVRE LMEE KKEE ITGT LRKD KTLL RDEK KMEK LKQK LHTD DELN WLDH GRTL REQG VEEH ETLL LRRK FFYS DQNV DSRD PVQL NLLY VQAR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | TLN; ILWEQ; talin-1; TLN1 |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cell surface, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, focal adhesion, ruffle membrane. |
Calculated MW: | 270kDa |
Observed MW: | 240kDa |
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Purification Method: | Affinity purification |
Gene ID: | 7094 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |