The TLK2 Polyclonal Antibody (CAB6770) offered by Assay Genie is a valuable tool for researchers studying TLK2, a key protein involved in DNA repair and cell cycle regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting TLK2 in human samples, making it ideal for Western blot applications.TLK2, a serine/threonine kinase, plays a crucial role in maintaining genomic stability and ensuring proper DNA replication. Dysregulation of TLK2 has been linked to various diseases, including cancer, making it a promising target for therapeutic interventions.
By using the TLK2 Polyclonal Antibody, researchers can gain insights into the functional role of TLK2 in cellular processes and disease development. This antibody is an essential tool for elucidating the molecular mechanisms underlying TLK2 activity, paving the way for potential therapeutic strategies targeting TLK2-related pathways. Order now to advance your research in genomics and cancer biology with the TLK2 Polyclonal Antibody from Assay Genie.
Product Name:
[KO Validated] TLK2 Rabbit Polyclonal Antibody
SKU:
CAB6770
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TLK2 (NP_006843.2).
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
11011
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] TLK2 Rabbit pAb (CAB6770) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
