The TLK1 Polyclonal Antibody (CAB14831) is a valuable tool for research focused on TLK1, a protein kinase involved in various cellular processes such as DNA repair and cell cycle regulation. This antibody is produced using rabbits, ensuring high reactivity with human samples, and is validated for use in Western blot applications. By specifically binding to TLK1, researchers can accurately detect and analyze this protein in different cell types, making it ideal for studies in molecular biology and cancer research.
TLK1 is a key player in maintaining genomic stability, making it a potential target for investigating diseases like cancer and other genetic disorders. By understanding the role of TLK1 in regulating DNA repair and cell division, researchers can develop targeted therapies and interventions to treat conditions related to genomic instability. The TLK1 Polyclonal Antibody offers a reliable tool for studying TLK1 function and its potential implications in disease progression and treatment.
Product Name:
TLK1 Rabbit Polyclonal Antibody
SKU:
CAB14831
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-230 of human TLK1 (NP_036422.3).
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9874
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TLK1 Rabbit pAb (CAB14831) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
