The TLE4 Polyclonal Antibody (CAB18345) is a valuable tool for researchers studying the TLE4 protein, which plays a key role in various cellular processes such as transcriptional regulation and development. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for use in Western blot applications. By binding to the TLE4 protein, this antibody enables accurate detection and analysis in different cell types, making it an excellent choice for studies in molecular biology and developmental biology.
TLE4, a transcriptional corepressor, is involved in regulating gene expression and suppressing transcriptional activity. Its role in developmental pathways and gene regulation processes makes it an interesting target for research in fields such as cancer biology, stem cell biology, and gene expression studies. By understanding the function and mechanisms of TLE4, researchers can gain insight into its potential role in disease processes and developmental disorders, paving the way for new therapeutic approaches and treatments.
Product Name:
TLE4 Rabbit Polyclonal Antibody
SKU:
CAB18345
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 173-243 of human TLE4 (NP_001269677).
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of beta-catenin-TCF complex.
Purification Method:
Affinity purification
Gene ID:
7091
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat lung, using TLE4 antibody (CAB18345) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
